Pro M (PROMK120PAW)

You say costs don't matter, but what does that mean? There are devices for thousands of dollars out there, and you'd need multiple in a home. My general suggestion is to find a balance between *total cost* (initial, plus ongoing filters, plus electricity) so you can maximize the benefit and not feel pinched. Wirecutter previously did some studies on total costs - you can try to find them online, but it's been some years. If you really have no cost, just get the largest air purifier you can fit for each room and run it at the highest speed. Your home may feel like a wind tunnel, and that means it's working. For most people, Blue Air is a good balance in these various aspects. They are affordable up front, filters from the OEM aren't too bad (and generics are available on Amazon), and they have an outer washable filter (so you don't waste the expensive inner one on say, pet hair, etc.). If it were me, I'd get a large one for the room I sleep in, and at least one or two others. Ignore any automatic sensor based setting they offer. At night, or when you're in the room, you want it on the highest setting possible, and during the day, turn it down just one notch. You want the air flow to circulate and air to essentially be "scrubbed" by the filters. Remember this is only a secondary or tertiary method of cleaning in terms of priorities. Your best bang for your buck is washing your bedding weekly (including the comforter) in unscented detergent, vacuuming or sweeping, and having good airflow in your home to prevent dust and mold build up (leave bathroom and closet doors open). Use your A/C generously to keep humidity levels down in the humid months and for the sake of your sinuses, use a humidifier in the dry cold winter months if your climate has them.