Honeywell - HPA5200B

I use the large room honeywell air purifiers. The one I have now has been running 24/7 for the last 5 years or so and is still trucking along. I use it because my wife and son smoke weed and smoke bothers me. It does a good job getting rid of the smoke and the amount of crap that is on the filter is amazing. I pretty much never have to dust.

I live in a tall loft with ciment ceilings and it produces a lot of dust. I got a large Honeywell HEPA air purifier and it works very well. The carbon pre-filter can be vacuumed and there is a thick layer of hair and dust every week. The inner filters I vacuum every month and change them once a year.

Just stay away from the Honeywell HPA models. They all develop a burning smell. I've swapped my 2 out a total of 6 times.

You can get a HEPA filter air purifier (Honeywell makes decent ones) to deal with PLA and TPU, they dont emit the toxic VOCs like ABS, Nylon and PC, but they do still emit fine particles. Having it enclosed like you do is going to prevent a lot of those fine particles from scattering through the room though so its a big help. As a rule I try to not have my printers in the same room I work, but if you must, that HEPA filter will help reduce the fine particles a lot. For the more toxic materials, absolute best bet is to create a negative air pressure environment while venting outside through a window or port. If you cant or want even more reassurance, running a carbon filter does a lot to help. There are specialized air purifiers for VOCs but theyre not cheap. A really good one you can get is from Heygears, called the GreenPrint Purification Unit. Just know it's specifically for VOCs as it doesn't trap particles, it destroys them (so you still want a HEPA for the fine particles). This air purifier doesnt need filters though, it doesnt trap VOCs like a carbon filter which can become saturated and need replacements. It actively breaks down VOCs, so it just runs indefinitely with full efficiency, no need to swap filters.

We have a Honeywell with a hepa filter. It has been great, though a tad expensive.