
Coway
Airmega AP-1512HH Mighty
Durable, effective, but struggles with strong odors.

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I've only used one. My son bought me a Honeywell HPA 5100B a couple of years ago. It's got a HEPA filter (change every 12th months), a prefilter (3 months), and optional odor and VOC filter (3 months). I use the first two. It's amazing how much visible crud is on the prefilters when they're pulled off. Crud isn't visible on the HEPA filter, but I'm breathing so I guess it's working. I don't have pets or other odor situation, so I don't use that filter.
Im doing good with Honeywell insight (largest size up to 500 sf). The filters arent cheap to replace but are HEPA & widely available. The only thing I don t like is you cant open it up to clean the vents.
Yes. I have Honeywell HEPA units in multiple houses. 24/7.
Honeywell. Their HEPA air purifiers routinely test out as the most effective and they make units made for spaces that large (I have one, it's such a relief during wildfire season). They aren't the quietist or the prettiest, but they don't need to be because they work. If you'll allow me on my soap box just a sec, please don't spend your money on popular "technologies" like ozone, static electricity, magnetized, etc. They don't work. What works is certified HEPA filters, H13 or H14.
For reasonable VOC removal there are only 4 players I know in the market which offer products which have the minimum 10 pounds of sorbent media: Airpura, Allerair, Austin, IQAir. Wildfires product a huge mix of chemicals - from the vegetation, contents of burned buildings, etc. There is no consumer solution that removes all VOCs. Each type of media is better at some chemicals, not so good or not effective at all with others. For the same reason there is no sensor that I know that will give you the level of all VOCs. These machines and filters tend to be expensive. I just upgraded my Austin units with Immunity Machine filters which cost \~$700 each. We were spared wildfire smoke this season but with AQI numbers breaking 100 I was able to keep my indoor values close to 0. I use Austin and IQAir VOC machines along with Honeywell and Whirlpool HEPA units, 3 filters per room.
Honeywell HEPA air purifiers. I have two: one in bedroom and one in the room where I spend most of my time watching TV, etc. Makes a difference for me.

Coway
Airmega AP-1512HH Mighty
Durable, effective, but struggles with strong odors.

Levoit
Vital 200S-P
Smart, quiet, great for dust, but some report filter smells.

Winix
5500-2
Great value, but noisy motor and Plasmawave issues.

Coway
Airmega Mighty
Durable, responsive auto-mode, but struggles with strong odors.

Winix
5510 & 5520
Good for allergies/pets, but carbon filter and Plasmawave issues.

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TEQOYA - Nomad

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CleanAirKits - Corsi-Rosenthal Box

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Austin Air - Healthmate Plus

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Winix - 5500-2

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Coway - Airmega 400

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Coway - Airmega AP-1512HH Mighty