
Logitech G
G600 MMO Gaming Mouse
Customizable MMO workhorse, durable, but discontinued and pricey.

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I have the same problem with the Deathadder V2 Pro. My hands are normal size, 21 cm. Razer is aiming for kids or asian market IMO. My case received a lot of downvotes from fanboys https://www.reddit.com/r/MouseReview/comments/1ajn4cd/how_is_it_possible_for_the_razer_deathadder_to_be/
I'm using a deathadder v2 pro wireless that I got for $5 2 years ago and spent 20 minutes fixing.
I have the Deathadder v2 Pro, Deathadder v3 Pro, Cobra Pro, Cobra Hyperspeed, and Viper v2 Pro. (And the Kysona Jupiter Ultra as my Viper v3 Pro clone) AMA
Look for an ergonomic mouse, like G502 series, Basilisk, or Deathadder, depending on weight preference. You can look for clones of any of those too. Deathadder Hyperspeed would be the Medium sized version, and the Pro the Large.
I use the Deathadder V2 Pro, same issue as you where the rubber on the thumb has worn down somewhat over the past 3 and a half years losing the texture but besides that I think its very comfortable and a very functional mouse, scroll wheel hasn't given me any issues yet and it be capable of being wired or wireless makes it very convenient as a college student hopping between a desktop and a laptop constantly, i've only just learned people have a bad opinion on razer but this was the best feeling mouse to me when i went to best buy back then to check their display stands, most of the others just felt clunky
FWIW I see the 502 suggested for people with big hands but I find the actual width of the part of the mouse you grip is not very large. Lots of things to consider, but I’ve got 20 cm x 11 cm hands and have settled on the DAV3 wired version. I’ve found the mouse width and desired shape (symmetrical vs ergo) to be the most important factors when looking for a mouse. Other mice I’ve tried and liked include the ZOWIE EC2 (look into EC1), Razer DAV2 Pro, and Logitech g403/703. Good luck!
I have relativeley big hands, more wide than long, but enough that I find small mouses quite uncomfortable. For the longest time the Razer Deathadder was my absolute favorite and I am getting a good lifetime out of them, my wired one is nearing 10 years (now office mouse) and the V2 Pro at home is around 5. Especially on the later, the rubbery material on the side got erroded away quite a bit. And don't get me started about their crappy synapse software. Long story short, I am looking für a new mouse/mice and was hoping for recommendations for larger mice. The xlite V3/V4 Large look like a good choice, and I would have just bought one to try out but it just isn't available anywhere for quite some time now (DE). Edit: I forgot to mention, I am mainly a palm gripper, might switch to „semi claw“ from time to time in cs but generally palm.

Logitech G
G600 MMO Gaming Mouse
Customizable MMO workhorse, durable, but discontinued and pricey.

VXE
R1 Series
Budget king: lightweight, great value, long battery life.

Hitscan
Hyperlight
Ultra-light (39g) for small hands; sensor is outdated.

Razer
Viper V3 Pro
Adaptable shape, optical clicks, but scroll wheel malfunctions.

Logitech G
G502 HERO High Performance Gaming Mouse
Durable, heavy workhorse with free-spin scroll; prone to double-clicking.

Ranked #1
Hitscan - Hyperlight

Ranked #1
Teevolution - Terra

Ranked #1
Razer - Viper Ultimate

Ranked #1
ROCCAT (Turtle Beach) - Kone Pro

Ranked #1
Logitech G - G600 MMO Gaming Mouse

Ranked #1
Razer - Naga Trinity